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Alternatively, the otic gel formulation is applied via syringe and needle, wherein the needle is inserted through the tympanic membrane and guided to the area of the round window or crista fenestrae cochleae

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The Day Before Surgery To ensure a smooth experience, take these important steps the day before your procedure: Arrange transportation to and from the dental clinic, as you wont be able to drive after sedation

The Need for New Formulations Because of these quite dramatic and potentially efficacious effects, and the urgency of the COVID19 pandemic, in addition to simply repurposing the original oral tablets, there have been efforts to develop new formulations and routes of administration for niclosamide, to validate them in preclinical studies, and clinically test niclosamide for COVID-19 (see this reference to clincaltrials.gov (35))